CAS 49851-31-2 2-Bromo-1-Phnyl-pentan-1-one

1. CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one Product Information:

2.What is CAS 49851-31-2?

at room temperature, add 500g (16.2 mol) to a 0.1 mL round-bottom flask phenylpentanone and 30.9g(0.3mol) of sodium bromide, after stirring well, add 24g(0.2mol) of 30% hydrochloric acid, and slowly add 19g(0.15mol) Dropwise 30% hydrogen peroxide, after the addition of
, continue the reaction for 1~2H, TLC monitoring after the reaction, stop stirring, static stratification, wash with saturated sodium carbonate, saturated
and brine, combine organic phase, concentrate and dry with anhydrous magnesium sulfate to obtain 2-bromo-1-phenyl-1-pentanone, bright yellow oily liquid, the yield was 95% and the purity was 98%(HPLC method).

3. What is CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one Used for?

2-Bromo-1-Phnyl-pentan-1-one can be used to prepare substituted imidazole derivatives with the following structure, which have high-efficiency KDM1A enzyme inhibitory activity and more than monoamine oxidase (MAO) selectivity, and can be used for histone demethylase activity Prevention or treatment of related diseases and disorders.

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