CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one

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CAS 49851-31-2 2-Bromo-1-Phnyl-pentan-1-one

CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one

1. CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one Product Information:

Product Name:2-BROMO-1-PHENYL-PENTAN-1-ONE
EINECS100-201-4
CAS NO:49851-31-2
Molecular Weight:241.12
Molecular Formula:C11H13BrO
Boiling Point:282.3±13.0 °C at 7600mmHg
Flash Point:42.5±7.2°C
Density:1.310±0.06 g/cm3(Predicted)
StorageStore in a dry and cool place
Purity:≥99%
Appearance:Yellow oil
Applications:Pharmaceutical intermediates, which can be used to prepare substituted imidazole derivatives with the following structure, which have high-efficiency KDM1A enzyme inhibitory activity and more than monoamine oxidase (MAO) selectivity, and can be used for histone demethylase activity Prevention or treatment of related diseases and disorders.

2.What is CAS 49851-31-2?

at room temperature, add 500g (16.2 mol) to a 0.1 mL round-bottom flask phenylpentanone and 30.9g(0.3mol) of sodium bromide, after stirring well, add 24g(0.2mol) of 30% hydrochloric acid, and slowly add 19g(0.15mol) Dropwise 30% hydrogen peroxide, after the addition of
, continue the reaction for 1~2H, TLC monitoring after the reaction, stop stirring, static stratification, wash with saturated sodium carbonate, saturated
and brine, combine organic phase, concentrate and dry with anhydrous magnesium sulfate to obtain 2-bromo-1-phenyl-1-pentanone, bright yellow oily liquid, the yield was 95% and the purity was 98%(HPLC method).

3. What is CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one Used for?

2-Bromo-1-Phnyl-pentan-1-one can be used to prepare substituted imidazole derivatives with the following structure, which have high-efficiency KDM1A enzyme inhibitory activity and more than monoamine oxidase (MAO) selectivity, and can be used for histone demethylase activity Prevention or treatment of related diseases and disorders.

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