CAS 49851-31-2 2-Bromo-1-Phnyl-pentan-1-one
1. CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one Product Information:
Product Name: | 2-BROMO-1-PHENYL-PENTAN-1-ONE |
EINECS | 100-201-4 |
CAS NO: | 49851-31-2 |
Molecular Weight: | 241.12 |
Molecular Formula: | C11H13BrO |
Boiling Point: | 282.3±13.0 °C at 7600mmHg |
Flash Point: | 42.5±7.2°C |
Density: | 1.310±0.06 g/cm3(Predicted) |
Storage: | Store in a dry and cool place |
Purity: | ≥99% |
Appearance: | Yellow oil |
Applications: | Pharmaceutical intermediates, which can be used to prepare substituted imidazole derivatives with the following structure, which have high-efficiency KDM1A enzyme inhibitory activity and more than monoamine oxidase (MAO) selectivity, and can be used for histone demethylase activity Prevention or treatment of related diseases and disorders. |
2.What is CAS 49851-31-2?
at room temperature, add 500g (16.2 mol) to a 0.1 mL round-bottom flask phenylpentanone and 30.9g(0.3mol) of sodium bromide, after stirring well, add 24g(0.2mol) of 30% hydrochloric acid, and slowly add 19g(0.15mol) Dropwise 30% hydrogen peroxide, after the addition of
, continue the reaction for 1~2H, TLC monitoring after the reaction, stop stirring, static stratification, wash with saturated sodium carbonate, saturated
and brine, combine organic phase, concentrate and dry with anhydrous magnesium sulfate to obtain 2-bromo-1-phenyl-1-pentanone, bright yellow oily liquid, the yield was 95% and the purity was 98%(HPLC method).
3. What is CAS 49851-31-2 2 bromo 1 phenyl pentan 1 one Used for?
2-Bromo-1-Phnyl-pentan-1-one can be used to prepare substituted imidazole derivatives with the following structure, which have high-efficiency KDM1A enzyme inhibitory activity and more than monoamine oxidase (MAO) selectivity, and can be used for histone demethylase activity Prevention or treatment of related diseases and disorders.
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